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ClarityPSA
Personalized prostate cancer screening companion
My biomarker values
Step 1 — PSA & Prostate Volume
PSAng/mL
Prostate volume (from MRI)cc
PSA density—ng/mL/cc
Step 2 — 4K Score
4K Score%
4K Density—score/cc
Step 3 — Other Biomarkers (enter any you have)
EPI Score (ExoDx)0–100
PHI Scoreindex
Step 4 — MRI Finding
PI-RADS 1–2
PI-RADS 3
PI-RADS 4
PI-RADS 5
Here is what current research suggests
Educational context only, based on PubMed-indexed research. Does not replace your urologist's clinical judgment. Bring these results to your next appointment and ask your doctor what they mean for you specifically.
Understanding your MRI report
Prostate MRIs are scored with the PI-RADS system (1–5). Here is what each score means in plain language — and what the published evidence says about next steps.
PI-RADS 1 or 2 — Very low / Low suspicion
Your MRI did not find anything concerning. Clinically significant prostate cancer is unlikely based on imaging alone. Your doctor may recommend continued PSA monitoring without biopsy.
PI-RADS 3 — Intermediate / Indeterminate
The "grey zone." The MRI found something equivocal. This is where secondary biomarkers like the 4K Score add the most clinical value — a high score may support biopsy while a low score may support watchful waiting. In a study of 2,538 men, biopsy rates in PI-RADS 3 patients differed by 34 percentage points based on 4K Score alone.
PI-RADS 4 or 5 — High / Very high suspicion
The MRI found a lesion with high likelihood of being clinically significant prostate cancer. Current AUA and EAU guidelines recommend biopsy in most men with these findings. Published data show 6–12x higher odds of proceeding to biopsy vs. a negative MRI.
Before your appointment — checklist
• Write down your PI-RADS score and lesion size from your report
• Note whether your report mentions the transition zone or peripheral zone
• Bring the CD or disc of your MRI images if they cannot be sent electronically — your urologist needs the actual scans, not just the text report
• Ask for a copy of the full written radiology report
• Write down 2–3 questions you want to ask your doctor before you go in
• Note whether your report mentions the transition zone or peripheral zone
• Bring the CD or disc of your MRI images if they cannot be sent electronically — your urologist needs the actual scans, not just the text report
• Ask for a copy of the full written radiology report
• Write down 2–3 questions you want to ask your doctor before you go in
PSA log
Log a new PSA value
Date
PSA valueng/mL
Note (optional)
No PSA values logged yet.
Add your first entry above to start tracking.
Add your first entry above to start tracking.
Evidence-based lifestyle guidance
Aerobic exercise
150+ min/week associated with slower PSA progression and improved quality of life on active surveillance.
Mediterranean diet
Associated with lower PSA progression rates and reduced risk of clinically significant prostate cancer.
Pelvic floor rehab
Pre- and post-operative pelvic floor training significantly reduces urinary incontinence duration after RALP.
Find a urologist near you
Enter your zip code to search for fellowship-trained urologists in your area via the AUA's verified physician directory.
💡 Tip: When searching, look for board-certified urologists with fellowship training in urologic oncology. Check that they have experience with prostate MRI-guided biopsy and the biomarker tests your doctor ordered.
Featured academic specialists
Dr. Sanoj Punnen, MD MAS MBA
Professor of Urologic Oncology · Desai Sethi Urology Institute, University of Miami
Prostate cancer 4K Score & MRI NCI-funded PIMiami, FL
Profile →
Dr. Mark L. Gonzalgo, MD PhD MBA
Chair, Dept. of Urology · Desai Sethi Urology Institute, University of Miami
Robotic surgery AUA Education ChairMiami, FL
Profile →
Dr. Dipen J. Parekh, MD
Founding Director, Desai Sethi Urology Institute · CEO, UHealth
Robotic oncology AUA Gold CystoscopeMiami, FL
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Dr. Chad R. Ritch, MD MBA
Associate Professor of Urologic Oncology · Desai Sethi Urology Institute
Bladder & prostate cancer AUA Leadership 2025–26Miami, FL
Profile →
Dr. Eric H. Kim, MD
Urologic Oncology · University of Nevada, Reno School of Medicine
Prostate cancer MRI-guided biopsyReno, NV
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Publicly listed academic urologists. Always verify availability and insurance directly with the institution.
Our mission
ClarityPSA was built to make prostate cancer screening easier to understand. Our goal is to provide patients with up-to-date education, published literature, and current AUA screening guidelines in one place, so they can arrive at their next appointment informed and ready to have better conversations with their care team.
TG
Timothy Guerard
Founder · Aspiring Urologic Oncology Surgeon-Scientist
Timothy is a first-year medical student aspiring to be a future Urologic Oncology Surgeon-Scientist. He led initial research into the 4K Density concept during his time as a research coordinator at the Desai Sethi Urology Institute prior to medical school. His work has been published first-author in Nature's Prostate Cancer and Prostatic Diseases, with additional contributions across peer-reviewed publications. He has presented original research at the AUA, SUO, WSAUA, and SMSNA.
Published research behind this app
Nature · PCAN · 2025 · First Author
4K Density: Adjusting the 4Kscore for prostate volume to improve risk stratification
PubMed 41107473 →
Journal of Urology · Oct 2025 · Contributing Author
Genomic Classifiers in Grade Group 1 Biopsy Cores — Miami Active Surveillance Trial
PubMed 40540647 →
Urologic Oncology · Nov 2024 · Contributing Author
Molecular and Diffusion Features for csPCa Identification in PI-RADS 3 Lesions
PubMed 38971674 →
Key supporting reference · PI-RADS & MRI
Negative predictive value of mpMRI — systematic review & meta-analysis
PubMed 32396916 →
ClarityPSA is an independent educational tool.
Not affiliated with any biomarker company.
© 2025 Timothy Guerard · claritypsa.org
Not affiliated with any biomarker company.
© 2025 Timothy Guerard · claritypsa.org